YOUNG-WOMEN Messages for September, 2000: Re: pediatric use of estrogen cream

Re: pediatric use of estrogen cream

From: R. Daniel Braun, MD (anonymous@obgyn.net)
Tue, 12 Sep 2000 20:43:08 -0500 (CDT)

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In reply to: matthew: "pediatric use of estrogen cream"

At Tue, 12 Sep 2000, matthew wrote: >
>My 10-yr old daughter has had a very small vaginal opening from birth,
>and various pediatricians suggested gently stretching the skin, which
>her mom did with her for 5 or 6 months at around age 5. It worked, and
>one day just opened up. We let it go, and now it's closed to about 3/4
>inch again.
>She has trouble with urine not completely draining, enough to spot her
>underwear and make her a little uncomfortable but not a serious amount.
>Recently her pediatrician suggested applying a bit of an estrogen cream,
>calle Premarin, to soften and maybe open up this skin again...her best
>guess is that it may open up during puberty anyway.
>We are concerned when we read the label warnings, which refer to using
>caution re estrogens and epiphyseal closure (something about bone
>growth?) in young patients. We also wonder if use of estrogens will
>prematurely hasten puberty.
>Any thoughts would be appreciated.

Short term use, I would think that a week or two would do it, is not going to affect epiphyseal closure. Especially when it is topically applied. If a full applicatorful of cream was inserted daily for two to three months, you might be beginning to possibly have a chance of a problem.

RDB

-- R.Daniel Braun, MD FACOG FOG

**Note: Opinions expressed here are for educational purposes only and, as such, do not constitute a physician-patient relationship. This information is not intended to supplant the need for you to consult with your physician prior to choosing therapeutic options and/or interventions.

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