WOMENS-HEALTH Messages for November, 1999: Re: action to estrogen? Dr.

Re: action to estrogen? Dr.

From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Sun, 7 Nov 1999 14:01:06 -0600 (CST)

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At Sun, 7 Nov 1999, Gina wrote: >
>Hi,
>I recently was prescribed estriodol vaginal compound cream
>for vaginal dryness. Since I am not supposed to take estrogen because
>of the blood clot risk, it was prescribed for me short term (2 weeks on
>2 weeks off, etc).

Estring may be an even beter choice. An estrogen impregnated soft plastic ring tht is left in all the time. Neglible absorption after the first 48 hours.

>At the same time I was prescribed progesterone compound cream to replace
>the "natural" plant based progesterone
>I had been using (which was working on my menopause symptoms but I
>wanted a known amount and wanted to know I was getting real
>progesterone).

Bot familiar with the term "progesterone compound". Progesterone is either one specific medication or another.

>I noticed an immediate difference. I became very irritable, anxious and
>jittery, depressed, and b*tchy to everyone. It was like an overdose of
>testosterone or something! Aggressive is an understatement.

Can't be sure with your situation, but progesterone can have androgen-like activity.

>So I believed it was the estrogen since it was the only thing totally
>different. I stopped taking it a few days ago and notice as each day
>goes by, those negative affects are fading. I am still taking the
>progesterone cream (and it's working better than the plant type, on my
>hot flashes!).

Interesting but confusing that you had these reactions to estrogen.

>I have never heard of a reaction like this to estrogen!

Me neither!

>Is there a
>reason for this? Is it a known side effect? Should I stop using it at
>all? I was thinking maybe I could use it
>only once a week (since I wanted to use it for vaginal dryness
>problems).
>Gina

Try the Estring and see if the same thing happens. My patients love it.

--
Harvey S. Marchbein, M.D. FACOG, FACS
Great Neck, New York

**Note:  Opinions expressed here are for educational purposes only
and, as such, do not constitute a physician-patient relationship.
This information is not intended to supplant the need for you to
consult with your physician prior to choosing therapeutic options
and/or interventions.

**Private emails cannot be entertained due to time constraints,
consequently no private emails will receive a response.

**Thank you for your understanding ;-)

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