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Re: ABO incompatablility-for Christine Smith

From: Christine (anonymous@obgyn.net)
Fri, 5 Nov 1999 08:14:10 -0600 (CST)


At Thu, 04 Nov 1999, JHC wrote: >
>Christine,
>I have typed this message twice in the last few days and for some reason
>it has not appeared on the list as a message.
>Anyway, you asked in your response (by the way thank you for responding
>to my question) if the woman that donated eggs to me had a type and Rh
>done. The answer is, yes, but the information was not available to me
>when I chose her as a donor (she was anonymous to me). I asked prior to
>the embryo transfer if blood type could present a problem and they said
>since I was Rh +, it should not be a problem.
>I read your answer to Bryce's post and it sparked another question. When
>I talked to my son's pediatrician about blood incompatablilities he
>mentioned that certain antibodies could also result in hemolysis of red
>cells and jaundice. He said that he would be interested in having a
>more comprehensive blood workup of our donor. I know in the past that
>type and Rh are usually the only things that they look at in pregnancy,
>but are other antibody incompatabilities a reasonable worry?
>
>Thank you for all of your good information.
>
>Regards,
>Jclarke

Hi again! IVF was in its infancy when I was working in this field but if I am thinking correctly, the comprehensive blood workup should be on you. Even though it was a donor egg, it is your immune system the baby is affecting. An antibody screen in you would detect antibodies you might now have. A type of the donor's blood cells would determine if she had the corresponding factor. (since it is the same donor she would have to have it if you have the antibody, unless you have received blood or were ever pregnant) Even a type of your husband's cells would give an idea about possibilities. But unless you have an antibody, I don't see where all of this would be necessary. Of course, there could be special circumstances where it would that I'm not aware of.

Chris S.




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