WOMENS-HEALTH Messages for October, 1999: Re: Post-hysterectomy followups

Re: Post-hysterectomy followups

From: Vera (anonymous@obgyn.net)
Sun, 31 Oct 1999 06:42:47 -0600 (CST)

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In reply to: Mamaw: "Post-hysterectomy followups"

At Sat, 30 Oct 1999, Mamaw wrote: >
>I was diagnosed in August with complex endometrial hyperplasia with
>atypia. I had a total hysterectomy with bladder repair two weeks ago
>and was diagnosed with endometrial cancer, Stage 1B.

Okay, do you also know the histological grading and the subtype of your endometrial cancer ? Both histological grading and the subtype are the important prognostic factors in patients with endometrial cancer.

>If the cancer were to spread, and I don't see how
>since it was not invasive, how or where would it be likely to occur?
Endometrial cancers of any grade are almost never associated with lymph node spread, as long as there has been no myometrial invasion. After myometrial invasion occurs, the incidence of pelvic and aortic lymph node spread is directly proportional to the depth of invasion and the degree of differentiation (histological grading). In your case, you have a stage 1B endometrial cancer. Stage 1B means that endometrial cancer cells of any grade (grade 1,2,3) have invaded less than one-half of the myometrium.

Undifferentiated cancer cells (grade 3) may spread to the pelvic and aortic nodes, while still confined to the superficial myometrium. And, upper abdominal peritoneal relapses are common in serous and clear cell subtypes. The other route of endometrial cancer spread is via the bloodstream (to the lungs), but this is uncommon for endometrial cancer limited to the uterus.

--
Vera, S.Ked.
Fifth year medical student
Diponegoro University
INDONESIA

Next message: Gretchen: "Yeast Infections Questions"
Previous message: Vera: "Re: ovarian cyts/fluid"
In reply to: Mamaw: "Post-hysterectomy followups"

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