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Re: AGCUS pap after LEEP procedure for severe dysplasia

From: Shannon (anonymous@obgyn.net)
Sat, 3 Jul 1999 06:49:59 -0500 (CDT)


Thank you Dr. Shanahan for responding to my question so quickly. A couple more for you, if you don't mind. If my LEEP pathology showed severe dysplasia with negative margins, ECC being negative, what are my odds of having residual dysplasia being the cause of AGCUS? Doesn't the LEEP actually take a portion of the endocervical canal too (wouldn't my LEEP pathology be indicative of the problem)? I guess what I really want to know, is what are my odds of having adenoca or something even though my LEEP and ECC were done just three months ago and had no glandular cell abnormalities whatsoever? I am on oral contraceptives which I thought might be somewhat protective from uterine cancer. I also have never had any abnormal uterine bleeding. I have, however, had AGCUS last year, 6 weeks postpartum. The colpo and ECC came back fine. The EMB showed hyalined villi etc, and I passed retained placenta shortly after. No AGCUS until now. Could the retained placenta issue have anything to do with the current result? Thanks again! Have a great Fourth!

At Sat, 3 Jul 1999, Kelly Shanahan, MD wrote: >

>At Fri, 2 Jul 1999, Shannon wrote:
>>
>>Hi-I'm 30 years old and recently had a pap done that came back AGCUS. I
>>am 13 weeks post-LEEP for CINIII. My recent colpo showed nothing. Could
>>this pap result possibly be the result of a cervix that is still
>>healing? I have had three ECCs in the past year (one with the LEEP
>>procedure, margins being negative for dysplasia) and they all came back
>>negative. SO, I have an appointment to have another ECC and endometrial
>>biopsy next week. Are AGCUS results uncommon after LEEPS or are they
>>possibly not even related. Any help would be appreciated. This
>>troubles me, and I actually thought that I was done with all this mess
>>until this. Thanks.
>
>AGSUS is Atypical Glandular Cells of Undetermined Significance -- you
>are scheduled for the appropriate evaluation -- endocervical currettage
>(ECC) and endometrial biopsy. These two areas are the potential source
>for the atypical glandular cells. AGCUS is not as common as ASCUS
>(atypical squamous cells). Your AGCUS may be related to the LEEP in
>that you may have a process which has affected both types of cervical
>cells, or you may have an unrelated process in hte uterine cavity -- or
>even nothing wrong at all -- "undetremined significance" means we don't
>really know what the course would be if left uninvestigated or untreated
>-- all AGCUS signifies is that we have to look furhter to find out if
>there really is a problem in the first place.
>
>It sounds as if your doctor is following and treating you appropriately.
>Good luck.
>
>--
>Kelly Shanahan, MD, FACOG
>S. Lake Tahoe, CA
>
>note: Opinions here are for educational purposes only. This information is not intended to supplant the need for you to consult with your own physician. It cannot take the place of a face to face consultation and examination.
>Sorry, but private e-mails will not be answered -- especially now that I have a new baby to take care of!!
>




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