WOMENS-HEALTH Messages for March, 1998: Re: Autoimmune thyroiditis and miscarriage

Re: Autoimmune thyroiditis and miscarriage

From: Kelly Shanahan, MD (anonymous@obgyn.net)
Mon, 9 Mar 1998 20:53:51 -0600 (CST)

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In reply to: Liz: "Autoimmune thyroiditis and miscarriage"

At Sun, 8 Mar 1998, Liz wrote: >
>I have two questions concerning the affect between autoimmune
>thyroiditis and the incidence of miscarriage.
>1) From what I understand, there is an increased incidence of having NK
>(killer) cells which can attack the placenta and the fetus in people who
>also have antithyroid antibodies. Any idea what percentage of people
>with increased antibodies would have these killer cells?

I'm not sure -- have some info on NK at the office. One of the most informative sites regarding natural killer cells and alloimmune and autoimmune repetative miscarriage comes from Dr Beer's site (of course the URL is at the office too!) -- try doing a search for Dr Beer's name.

I have had 2 >miscarriages in the past year. My TSH was 43 and my antithyroid
>antibodies were 99 right after the first one.
>2) How common is it to have sudden onset of "wierd cycles" after
>regulation for hypothyroidism is instituted?

It's very likely for there to be changes in your cycle due to all teh fluctuations in hormone levels as your thyroid meds are adjusted.

During this summer, my >thyroid levels went from low to high to normal to low to norma1. During
>that period of time, my cycles were normal as they had been even when
>the thyroid had not been treated. In September, I had crampy
>prementrual feelings right after ovulation. Two weeks later, when a
>period was due, I had every indication physically of ovulation again,
>along with 3 days (normal being6-7) of light bleeding. Ten days later,
>there were 5 days of spotting which progressed into 6 more days of what
>seemed to be a normal period (occuring when on my normal schedule I
>should have been ovulating). Two weeks later, I had a normal ovulatory
>phase and became pregnant. I lost the baby 11 weeks later---missed
>abortion. What is the likelyhood of this wierd pattern being a delayed
>reaction to the fluctuations of thyroid mid summer and could they, and
>the hormone imbalance they would reflect, be responsible for me not
>being able to carry that pregnancy?
>Thanks for any insights!

It's certainly possible. Good luck to you for a healthy baby.

--
Kelly Shanahan, MD, FACOG
S. Lake Tahoe, CA

note: Opinions here are for educational purposes only. This information is not intended to supplant the need for you to consult with your own physician. It cannot take the place of a face to face consultation and examination.
Sorry, but private e-mails will not be answered.

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In reply to: Liz: "Autoimmune thyroiditis and miscarriage"

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