WOMENS-HEALTH Messages for March, 1998: Re: action to raloxifene

Re: action to raloxifene

From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Sun, 1 Mar 1998 14:48:00 -0600 (CST)

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In reply to: Carolyn: "reaction to raloxifene"

At Sun, 1 Mar 1998, Carolyn wrote: >
>I am a 56 yr old woman, post menopausal, no period for 5 yrs. I had
>very little problems going through menopause, no hot flashes, no vaginal
>dryness. I took premarin/provera for about 1 yr 3 yrs ago, but stopped.
>Didn't like the way if made me feel. PMS like symptoms all the time.
>However, I have elevated cholesterol and am about 50 lbs overweight. On
>doctor's recommendation I began taking raloxifen 2/98. After five days
>on the medication I had hot flashes,

According to Lilly studies (the company that produces Evista) the baseline hot flushes rate is 18% and with Evista is increases 6-8 %.

>swollen breasts

According to Lilly, this should not be related since this Selective Estrogen Receptor Modulator should have no effect onthe breast. Then again, I can't give you another reason for your symptoms.

>and developed
>shingles.

Shingles is herpes zoster (chickenpox) being reactivated from the ganglia of nerve roots where they lie dormant for many years. Thisis an immunity thing and I've seen no information implicating Evista in this one. I agree with your doctor.

>I stopped taking the medication. My doctor says the shingles
>has no relation to the raloxifen. Any input on side effects of
>raloxifen?
>
>--
>Carolyn N.
>

Discuss tryiing the medication again if the advantages outweigh the disavantages for you. BTW, Lilly says the hot flushes reach baseline level in a few months.

--
Harvey S. Marchbein, M.D. FACOG
OBGYN.net U.S. Representative, New York
Great Neck, New York
http://www.obgyn.net/states/bios/marchbein.htm
http://www.obgyn.net/women/advisors/harveym.htm

**Note:  Opinions expressed here are for educational purposes only
and, as such, do not constitute a physician-patient relationship.
This information is not intended to supplant the need for you to
consult with your physician prior to choosing therapeutic options
and/or interventions.

**Private emails cannot be entertained due to time constraints,
consequently no private emails will receive a response.

**Thank you for your understanding ;-)

Next message: Kelly Shanahan, MD: "Re: GBS and vag exams"
Previous message: MN: "Re: epidurals ... birth experiences from 'older gal'"
In reply to: Carolyn: "reaction to raloxifene"

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