WOMENS-HEALTH Messages for January, 1998: Re: Clomid, PCO, and ovarian cancer

Re: Clomid, PCO, and ovarian cancer

From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Sat, 31 Jan 1998 23:32:55 -0600 (CST)

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In reply to: Amy: "Clomid, PCO, and ovarian cancer"

At Sat, 31 Jan 1998, Amy wrote: >
>I have been on 50 mg Clomid for 5 cycles (and 4 cycles a few years ago).
>No pregnancy yet, and an HSG on Wednesday showed clear tubes, although
>my lack of ovulation is due to suspected PCO.

Without ovulation, the possibility of increasing the dose of Clomid to 100, 150 and depending upon your weight, higher doses may be appropriate. The possibility of Glucophage and Clomid as a combo has a successful ovulation rate of 89%.

>My paternal grandmother
>died of ovarian cancer in 1993. I am worried about continued use of
>Clomid, and the risk of ovarian cancer. Should I be worried?

This information about infertility drugs and ovarian cancer has been refuted in several articles.

>How long
>can I safely go on using the clomid?

The Clomid doesn't do it. It may or may not be the fact that some inability to ovulate is the culprit but this still has to be delineated.

>My husband will be having a semen
>analysis (though a previous one showed a count of 150 mil, with no
>problems), so as long as that turns out ok, I assume my doctor will
>continue prescribing clomid for me. Any insights, advice, suggestions?

Amy,

Look into higher doses of Clomid and/or adding Glucophage.

--
Harvey S. Marchbein, M.D. FACOG
OBGYN.net U.S. Representative, New York
Great Neck, New York
http://www.obgyn.net/states/bios/marchbein.htm
http://www.obgyn.net/women/advisors/harveym.htm

**Note:  Opinions expressed here are for educational purposes only
and, as such, do not constitute a physician-patient relationship.
This information is not intended to supplant the need for you to
consult with your physician prior to choosing therapeutic options
and/or interventions.

**Private emails cannot be entertained due to time constraints,
consequently no private emails will receive a response.

**Thank you for your understanding ;-)

Next message: Harvey S. Marchbein, M.D.: "Re: Ovulatory pain"
Previous message: Harvey S. Marchbein, M.D.: "Re: cerclage procedure"
In reply to: Amy: "Clomid, PCO, and ovarian cancer"

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