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Re: Cervical dysplasia and HPV

From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Sat, 31 Jan 1998 23:23:48 -0600 (CST)


At Sat, 31 Jan 1998, Jeannette wrote: >
>I have been dealing with cervical dysplasia for the past ten years,
>through two successful pregnancies. Diagnosis and treatment have
>included many colposcopies, two cryosurgeries and LEEP surgery (removal
>of cervical tissue with hot wire) in July 1997. Followup to that LEEP
>surgery has not been encouraging. Another pap and colposcopy biopsies
>have shown moderate to severe cervical dysplasia. My doctor suggested a
>cone biopsy or a hysterectomy. My doctor believes that my situation is
>probably caused by the human papilloma virus (HPV). Research has led me
>to some info about the HPV - that there are over 100 varieties of which
>maybe 3 have high malignant potential. If I have one of the varieties
>that does not have high malignant potential then I could see living with
>my uterus and returning for many pap smears a year. This seems
>reasonable to me. My doctor and their lab, however, don't seem familiar
>with the possibilities of typing my biopsies for HPV type. What do you
>think? Does anyone have information on this? Thank you!

You can subtype the HPV but as we've read before, there's no guarantee that the low risk HPV won't have some HPV around that is not diagnosed and visa versa.

Studies have shown that the recurrence rate of the abnormalities you've mentioned are no different with cone biopsy or hysterectomy because the HPV also affects the vagina left after the hysterectomy. Discuss this info with your doctor. Most people would not do a hysterectomy but your case is very unique and the possibility has to be looked upon with the risks, benefits and alternatives.

--
Harvey S. Marchbein, M.D. FACOG
OBGYN.net U.S. Representative, New York
Great Neck, New York
http://www.obgyn.net/states/bios/marchbein.htm
http://www.obgyn.net/women/advisors/harveym.htm

**Note: Opinions expressed here are for educational purposes only and, as such, do not constitute a physician-patient relationship. This information is not intended to supplant the need for you to consult with your physician prior to choosing therapeutic options and/or interventions.

**Private emails cannot be entertained due to time constraints, consequently no private emails will receive a response.

**Thank you for your understanding ;-)






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