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endometrial biopsy and false negative test resultsFrom: Sharon (anonymous@obgyn.net)Sat, 31 Jan 1998 00:11:20 -0600 (CST)
Recently I asked whether it was preferable to take pathology from tissue taken during a hysteroscopy or to do a D&C to determine whether treatment for hyperplasia has been effective. I have been diagnosed with endometrial hyperplasia and polycistic ovary syndrom (PCOS) that was discovered by an hysteroscopy that my doctor wisely insisted on even though an endometrial biopsy came back normal just six weeks earlier. Question: Given the false negative that came back on the endometrial biopsy before, when I complete my 4 month Provera treatment, can I rely on the results of another endometrial biopsy to accuratly show if the hyperplasia has been taken care of? My doctor mentioned that it is unusual for a endometrial biopsy to be so far off the mark, but has suggested that in my case we should do another hysteroscopy and take tissue for pathology, or a offce or outpatient D&C. Any suggestions on which of these two options would give me the best chance of accurate results? [My Thanks to Dr. Marchbein who provided great information to my previous posting]
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