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Re: antiphospholipid antibodies

From: Jeannine Fitzgerald, RN (anonymous@obgyn.net)
Fri, 16 Jan 1998 19:17:54 -0600 (CST)


At Mon, 19 May 1997, Harvey S. Marchbein, M.D. wrote: >
>At Mon, 19 May 1997, Kelly wrote:
>>
>>At Sun, 18 May 1997, MO wrote:
>>>
>>>Hi
>>>
>>>We are looking for information on immunological barriers to pregnancy,
>>>specifically the APA test, which some doctors only recognize if it
>>>includes at least 18 specific sub tests.
>>>
>> can anyone tell us what
>>>the names are of the individual items so we can ask the lab?
>>
>>The components are(at least in the lab we use):
>> Lupus anticoagulant
>> cardiolipin IgG, IgM and IgA antibodies
>> phosphatidyl serine IgG, IgM and IgA antibodies
>> phosphatidic acid IgG, IgM and IgA antibodies
>> phosphatidyl ethanolamine IgG, IgM and IgA antibodies
>> phosphatidyl choline IgG, IgM and IgA antibodies
>>
>>That's only 16, but it is what is included in the "expanded APL
>>syndrome" evaluation here.
>
>Dr. Shanahan, as always ;-) , is quite right. Many articles, of late,
>have discussed the "fact" that the only important antibodies in this
>category are Anti-cardiolipin antibody (ACA) associated with repeated
>miscarriages, future blood clotw and other problems.......and lupus
>anticoagulant (LAC). Many investigators feel that the other antibodies
>are of little to no importance. Or, as my son would say "Slim to none,
>and slim just left town!"
>
>--
>Harvey S. Marchbein, M.D. FACOG, FACS
>OBGYN.net U.S. Representative, New York
>Great Neck, New York
>http://www.obgyn.net/states/bios/marchbein.htm
>http://www.obgyn.net/women/heroes/harveym.htm
>
>*Note: Opinions expressed here are for educational purpose only.
>This information is not intended to supplant the need for you to
>consult with your physician prior to choosing therapeutic options.
>

--
I am suring to find info on ACA but find it only in relationship to fertility.  I am interested in other reasons that this antibody would appear.  My daughter is 32 years ol an having micro-strokes as a result of this "rear" blood disordere.  Please if you have any infomation or can send me in the right direction I would appreciate it. Thanks!



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