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Re: over-active thryroid in pregancy

From: Patti (anonymous@obgyn.net)
Tue, 11 Nov 1997 17:34:23 -0600 (CST)


At Sat, 8 Nov 1997, Harvey S. Marchbein, M.D. wrote: >
>At Sat, 8 Nov 1997, Lila wrote:
>>
>>My daughter has an over-active thryroid gland and was taking the thryoid
>>medication for pregnant women, I do not remember the name of the drug.
>>She suffered a extemely severe drug reaction to this pill and was
>>hopitalized because she became sick with a sore throat and it was
>>discovered she had a 0 count of white blood cells. They had to get her
>>white blood cell count up as she had no immune system. My question is
>>will this effect the baby. She was about three months pregnant at the
>>time. She has had an ultra-sound and the baby was fine. Should I be
>>worried about any other complications due to this drug reaction.
>
>The thyroid problem and no white blood cells are seemingly two separate
>problems. This is too complex for an internet diagnosis. A fetal
>maternal medicine expert in needed to get a full picture of all the
>implications.
>

I think what Lila may be referring to is a relatively rare side effect of taking propylthiouracil or methimazole for hyperthyroidism--agranulocytosis. Symptoms include sore throat, fever, malaise. I am not a medical doctor, but I know "a bit" about pregnancy and hyperthyroidism as I have it. My guess would be that this shouldn't affect the baby, it would only affect the mother's ability to fight off an infection.

Was your daughter hyperthyroid before she got pregnant? I was not, it seems to be pregnancy induced. It was first diagnosed in my second pregnancy, went away after I delivered, and now is back with my third. This presentation seems pretty rare, so I have hesitated posting any questions about it. Any real doctors want to field them?

--
Patti, Georgia (USA)



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