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Re: ovarian cancer riskFrom: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)Sun, 9 Nov 1997 23:51:33 -0600 (CST)
At Sun, 9 Nov 1997, Jiayuan wrote: > >Dear Doctors, > >I have a question about my mother. She would like to know her >susceptibility to ovarian cancer and decide whether to accept preventive >ovarian operation or not. > >My mom is 53 years old. She was diagnosed uterus myoma last year based on >major complaint of prolonged period and B-ultrasonic imaging. Her mother >, my grandma died of ovarian cancer in 1985 at the age of 62. The type of >the tumor is not clear. The chief doctor of department of Gynecology >suggested my mom to have preventive Ovarian-Hysterectomy operation since >the ovarian tumor grows very fast and it usually turns out to be too late >when discovered. Take her family history, my grandma and my grandpa(He >died of cancer too, the type is yet unkown)into consideration, the >chances my mom got an ovarian tumor is rather high. It is better to >prevent it before it happens. > >What`s the indication of preventive operation of ovary and uterus? Is my >mom good candidate for such operation? As a medical student, it is a >rather big operation in gynecology. And the patient has been through the >operation suffer menopause syndrome from the inbalance of hormones. My >mom now still has normal menstral period and she was diagnosed ST segment >decrease(EKG) and sometimes feels palpitation. > >Please evaluate my mom`s situation and your opinion is very important for >us to make the decision. > >If you need more information about my mom please feel free to write to me. > >Thank you very much. > >Best wishes, >James Tong With one first degree relative having ovarian carcinoma, your mom's risk of ov. ca is approximately 15% If your mother wishes to get Brca 1 & Brca2 testing, there is an increased incidence if positive (possibly 60%). Another option is to follow with transvaginal color doppler sonography and CA125 (blood test) used together to find early cancers. This is not a perfect screening test, even for people with a family history, but some feel it's better than nothing. Not all gyn. oncologists agree. Major surgery is still major surgery with attendant risks. Also, there are cases of familial ovarian cancer in which the ovaries have been removed and the patient still get an ovarian cancer-like disease. This is all the info we have at this time. Good luck with Mom and best wishes for her good health.
-- Harvey S. Marchbein, M.D. FACOG, FACS OBGYN.net U.S. Representative, New York Great Neck, New York http://www.obgyn.net/states/bios/marchbein.htm http://www.obgyn.net/women/advisors/harveym.htm
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