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Re: Hot flashes....

From: Catalin (anonymous@obgyn.net)
Tue, 3 Jun 1997 21:29:09 +0300 (GMT+0300)


On Tue, 3 Jun 1997, Laurie Lovely wrote:

> >>From the above mentioned "drugs", I have experience with only clonidine
> >(0.05 mg bid) and I used it *only* in patients with flushes due to
> >rosacea.
>
> That dose could be increased considerably if not effective.
>

But, what about hypotension? I asked not just to argue, but I'm very curious how far did you go with the dosage without significant side effects.

> There are several RCT's showing clonidine to be more effective than
> placebo in controlling hot flushes due to estrogen deprivation, but I
> don't know about flushes due to rosacea.

This is really interesting. I wasn't aware of these.

> The clonidine patch is well-tolerated
> and effective.

What concentration of clonidine does it contain? Is it approved by the FDA for this indication?

> Laurie Lovely, MD
> RE fellow, UNC-Chapel Hill

--
Catalin Popescu
Dermatologist



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