WOMENS-HEALTH Messages for May, 1997: Re: antiphospholipid antibodies

Re: antiphospholipid antibodies

From: Kelly (anonymous@obgyn.net)
Tue, 20 May 1997 23:17:53 -0500 (CDT)

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At Tue, 20 May 1997, MO wrote: >
>Oops, the more I learn the more I realize I don't understand. I was
>told that there are only two labs or so that do a "full APA panel" (but
>the 16 ithems the two doctors mentioned seems pretty close). One is Dr,
>Mantzner's (near San Diego) and one may be A Dr. Beer's.

Yet I wonder, >do they do something that other labs don't? Is it that they test for
>some things others don't?

They both believe very strongly in autoimmune and alloimmune causes for infertility and pregnancy loss (the alloimmune stuff is very controversial according to what I have read and what the REs I've talked to have said). Both labs do more esoteric tests (like natural killer cell assays, HLA typing of both partners, and some others that are so out of the mainstream I can't even remember what they are)

I realize that >there are differences of opinion on infertility techniques and I try to
>keep an open mind

Very good idea, because there is a lot of controversy about what works and what is hocus-pocus.

It means all the more because I >have to decide whetherto trust the test results if I get the APA done
>here in Japan.

If you are comfortable and confident in your RE I would trust his/her judgement regarding your lab.

I just had the full antiphospholipid panel done because I've had 2 miscarriages and my anticardiolipin was at the upper limits of normal. One component of the 16 (the anticardiolipin IgA) was weakly positive. It really didn't provide much more info than the basic anticardiolipn and lupus anticoagulant and it was quite expensive. I think the basics are probably enough (my RE told me the same thing, but we doctors are terrible patients) >

-- Kelly Shanahan, MD, FACOG S. Lake Tahoe, CA

note: Opinions here are for educational purposes only. This information is not intended to supplant the need for you to consult with your own physician. It cannot take the place of a face to face consultation and examination.

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