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Re: LupronFrom: Susan (anonymous@obgyn.net)Tue, 29 Apr 1997 16:05:15 -0500 (CDT)
At Mon, 28 Apr 1997, SOS wrote: > >At Mon, 14 Apr 1997, Joella wrote: >> >>At Tue, 18 Mar 1997, Lori wrote: >>> >>>I am 28 years old and have endometriosis. I had Laser surgery in 1988 >>>and May 1996. The severe pains never went away with the last surgery so >>>my doctor put me on continuous birth control with no periods. I started >>>the continuous birth control in May 1996 and by Sept the pain was >>>finally gone, but the cramps started coming back in Feb and are now >>>worse than ever. I saw a new doctor today who wants to try Lupron. My >>>choice of treatment is a hysterectomy. I have two children and don't >>>want anymore. The pain is affecting my marriage and my children when I >>>get home from work I go straight to bed with a heating pad and pain >>>pills. Can any tell me more about Lupron? Has anyone taken the six >>>months of injection and not have the endometriosis return? Has anyone >>>had a hsysterectomy due to endometroisis before 30 years old? >> >>Lori, I had a laparoscopy in January of 1996 after experiencing severe >>constant pain. I have always had bad cramps and was put on the pill to >>alleviate them. I was found to have endometriosis, and my doctor >>prescribed three months of Lupron shots. He likes to try three months, >>instead of six, because he has found that three usually work, and then >>you can always have three more later if you need them, because you can >>only have six in your life from what I've been told. While I was taking >>the shots, I experienced some pain and hot flashes. I did not have any >>of the mood swings or other side effects. Since my last shot, I have >>been pretty much pain free. I still get cramps during my period >>occasionally, but they are much better, and I am off the pill. I have >>not had any children yet, but I am told that when I do, this will get >>better. Of course, that doesn't help your situation since you already >>have kids. Good luck! > >I'm 34 & have had my kids. I tried two doses of Lupron and basically >loved it. Although I did have the flashes, my moods were level and my >SEVERE cramps had been alleviated. Weight loss was a niceity too :) >Unfortunately, I'm now 2 years out from the Lupron therapy and facing >the same problems as before and considering a hyst. Of course this is >only my expericne, but I loved it. Good luck Ladies, Lupron and other GnRH agonists are approved by the FDA for use in managing anemia due to fibroids, and nothing else. I opted to try it to reduce the pain and bleeding I had from fibroids and endometriosis even though I was not anemic (low red blood cell count.) It supresses the release of hormones in your pituitary gland that in turn reduce the level of estrogen secreted by the ovaries, and in essence causes temporary menopause. The biggest risk of these drugs is bone density loss due to sudden drops in estrogen in your blood stream. As you may know, bone loss can lead to osteoporosis if you lose enough mass over the years. Bone loss is the reason that the FDA has prohibited the use og GnRH agonists for more than 6 months, as the risk of permanent damage to your bones is too high. Weigh this risk against the theraputic value of it's use, and ask your doctor if low-dose estrogen supplementation during the course of Lupron is appropriate in your case. You can also tank up on foods high in calcium and other bone enhancing nutrients during treatment. Good luck!
-- Susan Boyles
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