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ONCOLOGY: Obesity Link to Ovarian Cancer (some evidence that hormones protected women) From: Hope Waltman (anonymous@obgyn.net) Thu, 8 Jan 2009 17:20:49 -0600 (CST) Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Hope Waltman: "PREGNANCY: Prenatal Nutrition, Postnatal Allergy Protection" Previous message: penni: "BREASTHEALTH: please help" Obesity Linked to Ovarian Cancer Excess estrogen may contribute to malignancy, study suggests MONDAY, Jan. 5 (HealthDay News) -- Obese postmenopausal women who have never used hormone replacement therapy may face an increased risk of ovarian cancer, compared to normal-weight women, a new study suggests. Interestingly, obese women who have used hormone replacement therapy (HRT) for symptoms of menopause may not face increased risk for this type of malignancy. The study findings are published in the Feb. 15 issue of the journal Cancer. The take-home message is a familiar one, experts said: Maintain a healthy body weight. "It's interesting that, in women who were exposed to menopausal hormones, there was some evidence that [hormones] actually protected them," he added. "It's, at best, a modest effect and not nearly as strong as the data with endometrial cancer. I'm not a fan of obesity, but I think, in this particular analysis, it's a pretty modest effect. It would be much more convincing if it were significant for the entire population." Study lead author Dr. Michael Leitzmann, of the National Cancer Institute, said one "possible reason for the observation that obesity might lead to increased ovarian cancer risk in women who have not used HRT versus women who have is that exogenous estrogens supplied by menopausal hormones fail to add further to the high background levels of endogenous estrogens among obese women." http://www.nlm.nih.gov/medlineplus/news/fullstory_73474.html Regards, Hope Waltman, WHF Moderator http://www.hopeforfibroids.org Next message: Hope Waltman: "PREGNANCY: Prenatal Nutrition, Postnatal Allergy Protection" Previous message: penni: "BREASTHEALTH: please help"

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