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Re: PCOS: PCOS and fertility

From: Walter Futterweit, MD, FACE,FACP (anonymous@obgyn.net)
Tue, 25 Mar 2008 18:10:58 -0500 (CDT)


The combination of clomid and metformin has been found to be a good tool in helping you ovulate. The live birth pregnancy rate would probably be helped with a 100 mg dose of clomid for 5 days and raising the metformin to 1500 or 2000 mg daily in divided doses. Keep your weight down, and try for at least 2-3 cycles with this regimen. Best of luck, Dr. Futterweit

At Tue, 25 Mar 2008, embryo wrote: >
>Hello,
>
>I am a 24-year old young woman with PCOS, otherwise healthy, not
>overweight, no insulin resistance/Type II diabetes. My free
>testosterone level is fine, but DHEAS is high (14.7umol/L), ratio of
>FSH:LSH is 1:2. I had teratoma removed from one of my ovaries in 2002
>and have recurrent cysts if there is no periods. I don't have periods
>unless they are chemically induced, and no ovulation as tested by Day 21
>progesterone level. I don't have acne, maybe few pimples from time to
>time.
>
>I got married recently and we are trying to have a baby. I am a PhD
>student and at the moment unfortunately, cannot afford expensive
>reproductive treatment or fees that fertility clinics charge. My
>general obstetrician prescribed me Clomid alone which didn't help, and
>by help I mean induce ovulation (my progesterone levels were 1.6 nmol/L
>on Clomid (50mg alone). We tried metformin(1000mg) plus Clomid (50mg),
>which seemed to induce ovulation (Day 21 progesterone was 10 nmol/L),
>but I didn't get pregnant. Given what I described above, what in you
>opinion should be the next step? Should I try with the same regimen
>another couple of months or go to more agressive treatments?
>
>Any advice, comment from your side is greatly appreciated.
>
>Sincerely,
>Natalie

--
Walter Futterweit, MD, FACP, FACE
Clinical Professor of Medicine, Division of Endocrinology
Mount Sinai School of Medicine, New York, NY 10029
http://www.aacehost.com/pages/page.php?r=716





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