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high estradiol + 20mm follicle on Day 3

From: jen (anonymous@obgyn.net)
Sun, 28 Sep 2003 13:20:02 -0500 (CDT)


I am just turned 46, childless, and TTC. I had an early miscarriage several years ago. I am waiting for a suitable cycle to try medication and IUI again. I had Clomid, Gonal-F and IUI in Feb.

Last week I had a v. short period (half-a-day proper flow; usually it is 2 days)and then a Day 2 FSH of 2.5 mIU and Estradiol 1,395 pmol/L (that's a UK measurement - I think the conversion ratio to US is approx 4:1, so 348?) Prolactin was also high at 992 mu. A scan on Day 3 showed a 20 mm follicle on the right ovary, and a 9 mm on the right. Estradiol on D3 was up again, to 1,570 (392).

Mostly I have high FSH (from 12 to 21) but normal Estradiol (150 pmol/L, or 37 in the US). Except for May, and last month, and now this month when it is much higher than ever before. I have been told high estradiol is pushing down the FSH - but it means the same thing: failing ovarian reserve. Is this right?

Is it unusual to have a 20 mm follicle on Day 3?

The RE said it wasn't a LUF or cyst. How can he be sure?

Thank you. Jen.






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