WOMENS-HEALTH Messages for September, 2003: Re: efudex for cervical dysplasia

Re: efudex for cervical dysplasia

From: R. Daniel Braun, MD (anonymous@obgyn.net)
Wed, 17 Sep 2003 15:57:00 -0500 (CDT)

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In reply to: Lucy: "efudex for cervical dysplasia"

At Wed, 17 Sep 2003, Lucy wrote: >
>My history is as follows:
>
>I am 28 years old and would like at some point the option of having a
>child. One year ago my pap came back showing high grade abnormalities
>with moderate dysplasia. My doctor performed a leep, and the biopsy
>showed that the lesions were in fact low grade. It also showed that
>some pre-cancerous tissue at the opening of the cervical canal had not
>been removed. I had two normal paps, and then last month my pap,
>confirmed by biopsy, came back showing low grade abnormalities. In
>part, I gather, because of the location (on/near canal), my doctoe
>performed another leep last week. The leep biopsy shows mild dysplasia,
>but my doctor wants me to go on a six-week regimen of efudex. I do not
>want to do this because a) it seems excessive for mild dysplasia and b)
>I have moderate eczema and am afraid of the pain and discomfort this
>treatment will cause me. I would like to ask what am I missing--what
>would make the efudex an appropriate treatment? Why would it be
>indicated?
>
>Many thanks.

A LEEP should be more than adequate treatment for mild dysplasia. Most oncologists have given up on efudex as a treatment for cancer because the side effects were so bad. Stopping smoking would be very beneficial in preventing a recurrence. 90+% of women with dysplasia smoke. It seems tro impair the immune system and allows the HPV to do whatever it does to cause dysplasia.

--
R.Daniel Braun, MD  FACOG   FOG
**Note:  Opinions expressed here are for educational purposes only
and, as such, do not constitute a physician-patient relationship.
This information is not intended to supplant the need for you to
consult with your physician prior to choosing therapeutic options
and/or interventions.

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In reply to: Lucy: "efudex for cervical dysplasia"

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