WOMENS-HEALTH Messages for December, 2002: Atypical leimyoma

Atypical leimyoma

From: Sidrah (anonymous@obgyn.net)
Tue, 17 Dec 2002 12:53:26 -0600 (CST)

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Reply: William McIntosh, MD: "Re: Atypical leimyoma"

I am 31 years old, female, married for the last five years. I have always had irregular menses and had taken progesterone therapy off and on to regularize them, but with out any success. Menstruation cycle remained irregular any where between 30-50 days We as a couple suffer from male factor infertility (congenitally absent Vas Deference) diagnosed only two years ago. On Ultrasound I have multiple fibroid uterus. We are contemplating fertility treatment in form of ICSI after surgical retrieval of sperm from my husband’s testis. Ultra sound in 2002 October showed increase of fibroid size to 41 mm from 20 mm median size. Myomectomy carried out on doctor’s advice to avoid problems in implantation after ICSI as the endometrial cavity was very tortous. Total number of 8 fibroids removed with two of the size of 51 mm. Postoperative ultra sound showed presence of fibroid seedlings Major concern now is Histopathology of fibroids Microscopic Description Sections shows proliferation of smooth muscle cells. These cells are pleomorphic with high N/C ratio and prommimant macronucleoli. One mitotic figure seen per 10 hpf Diagnosis Multiple uterine fibroids-Atypical leiomyoma

My question is if we opt for fertility treatment using gonadotropins, are we likely to increase the chance of aggravating atypical form into frank cancerous form. Should I go for the fertility treatment or go for Hysterectomy. Can we avoid hysterectomy at present?

We are very worried and I would very welcome your opinion at this stage. If you require the slides, I will be happy to courier at your address. With best wishes, Merry Christmas and a very Happy New Year.

Sidra Mahmood. E –Mail sidrahakbar@yahoo.com Address D-67 FFCL Goth Machi Sadikabad Pakistan Tel no 092300-9507196, 092702-786420-5667

Next message: Micha: "Re: Feel all alone can someone help?Pelvic Varicose veins"
Previous message: Fabio Fiorino, M.D.: "Re: Did I do the right thing with my pill?"
Next in thread: William McIntosh, MD: "Re: Atypical leimyoma"
Reply: William McIntosh, MD: "Re: Atypical leimyoma"

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