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Re: To Dr. Cristalli Re: shrinking uterine fibroids with prometrium or progesterone creams

From: anonymous (anonymous@obgyn.net)
Mon, 30 Sep 2002 08:28:52 -0500 (CDT)


At Sun, 29 Sep 2002, BJ wrote: >
>You are incorrect about the non-absorption of progesterone
>transdermally. The studies have been done and prove this. For example
>see K.J. Chang, T.T.Y. Lee, G. Linares-Cruz, S. Fournier, and B. de
>Lingieres. "Influences of Percutaneous Administration of Estradiol and
>Progesterone on Human Breast Epithelial Cell Cycle in Vivo." Fertility
>and Sterility 63 (1995):785-791.

>Even the abstract of this study says nothing at all about fibroids. In fact, the study concludes that progesterone "reduced the proliferation of normal breast cells in vivo". It's quite a stretch to say that natural progesterone will shrink fibroids. Especially since it is now known that the majority fibroids aren't fed by estrogen.

>At Sat, 28 Sep 2002, Bernard Cristalli MD wrote:
>>
>>At Fri, 27 Sep 2002, pat wrote:
>>>
>>>I would like to know if it is possible for me to be able to shrink
>>>uterine fibroids by using Micro-Nor or Prometrium on a daily basis. I
>>>would also like to know if these two products are the same as
>>>progesterone creams.
>>
>>---
>>
>>These 2 products are progestins (Prometrium is natural-like
>>progesterone). The cream is the same product but is unable to pass
>>beyond the skin.
>>Anyway they are quite unable to shrink any fibroid.
>>
>>--
>>*These comments are for educational purpose only. They can't replace an examination by your doctor.
>>* I won't have time to answer personal mails, please post to the forums.
>>
>>Bernard Cristalli MD AMACOG
>>AIHP - ACCA - Paris France
>>OBGYN.net Editorial Advisor
>>Urogynecology Editorial Advisory Board
>>http://www.obgyn.net/corresp/cristalli.htm
>>






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