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Re: To Abby Re: Hysterectomy-part 1

From: Victoria (anonymous@obgyn.net)
Tue, 3 Sep 2002 22:09:50 -0400

Dr. Mark Perloe, a leading noted reproductive endocrinologist, never mentions those as being factors. The route of the administration is what is mentioned as a factor, and its binding method in the bloodstream. Whether or not an MD prescribes it, a pharmacist mixes it, has no bearing on any of his answers. 

--
Victoria


http://forums.obgyn.net/ob-gyn-l/OBGYNL.0205/0317.html
Topical progesterone can be wonderful. 95% is metabolized to
hydroxyprogesterones with little protective effect. Yet, these metabolites can
bind to the Cl ion channel, like valium. Salivary and serum progesterone
correlations tend to be quite high.


http://forums.obgyn.net/ob-gyn-l/OBGYNL.0207/0039.html
Giving topical progesterone is worthless plain and simple. There are very large
amounts of 5 alpha reductase in the skin which will metabolize up to 98% of any
P administered topically. But they will feel good, since the 5 alpha reduced
progesterone will bind to the Cl ion channel receptor, the same place valium
binds.


From: anonymous@obgyn.net


I am curious, if progesterone cream prescribed by a doctor, compounded
by a pharmacist and paid for by insurance would be considered a placebo?



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