Re: to BJ about progest cream
From: anonymous@obgyn.net
Thu, 18 Apr 2002 15:31:43 -0500 (CDT)
BJ,
The article to which I was referring is:
http://www.wdxcyber.com/nbleed14.htm
BJ, can I email you offlist re some questions I have re progesterone
cream, menstrual cycles, endo, etc.? Or can I communicate with you on
this subject at the endo forum? I just don't want to bog down this forum
with "chat" as I think it may make it more difficult for the docs in
weeding through the mail.
Did you happen to gain weight, increase in acne/oily skin, etc. since
taking progesterone cream?
At Thu, 18 Apr 2002, BJ wrote:
>
>At Thu, 18 Apr 2002, anonymous@obgyn.net wrote:
>>
>>BJ, you have me totally confused! I read, at Dr. Rick's website
>>http://www.wdxcyber.com
>>that it is actually progesterone (I don't remember whether he said alone
>>or in addition to estrogen) which causes fibroids to increase/grow in
>>size?!?
>>I may also consider trying out the progesterone cream (just got off bc
>>pill a few months ago and STILL have not had a period). I, too, have a
>>history of endo/endo surgery.
>
>I am not surprised at your confusion. lots of that going around! Is
>this the information you read on that site? "As far as uterine fibroids
>go, the present theory regarding their development is that neoplastic
>transformation of normal muscle cells occur under the influence of many
>hormones, including E and P. Fibroids have receptors for both E and P.
>The exact stimulus for growth is UNCLEAR but may be related to relative
>levels of E and P." The last sentence refers to relative levels. That
>is what I have come to believe. The progesterone level is too low to
>balance the estrogen level so it is the estrogen, in my opinion, that
>causes the fibroid growth and the progesterone that inhibits it. What
>this says about receptors is also said about breast cancer but a
>receptor does not necessarily mean that the particular hormone causes
>growth. Binding of progesterone to progesterone receptors causes
>inhibition of growth.
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