Re: Post-surgical CA-125
From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Mon, 1 Apr 2002 20:25:15 -0600 (CST)
Although I'm at home and not with any reference manuals, there are at
last count, over 30 different problems causing elevated CA-125. Many
have to do with benign ovarian lesions as well as a variety of liver
problems. Endometriosis and fibroids are notable as well but with a
TAHBSO, it't not too likely.
Conditions such as endometriosis, normal pregnancy, pelvic inflammatory
disease, uterine fibroids, hepatitis, pancreatitis, and cirrhosis may
contribute to elevated levels of serum CA 125. Malignancies of breast,
lung, and gastrointestinal tract may also be associated with an
elevation of this tumor marker.
Hope this helps and write back anytime for more information.
Dr. M
At Mon, 1 Apr 2002, Dorrie wrote:
>
>My mother died of ovarian cancer, and had a positive history of breast,
>lung and colon cancer. Her father died of colon cancer - no other
>cancers in family. Because of her history, her gyn onc recomended
>annual TVUs and CA-125. All went well for several years. Last year, my
>CA-125 was elevatedd - 90 and continued to rise to 210 -- I had a
>negative TVU (except some follicular cysts and a fibroid). Findings of
>colonoscopy, CT of chest, abdomen and pelvis, MRI and PET were also
>negative. Given history, I opted for a TAH/BSO in January. Pathology
>was negative for malignancy - full surgical exploration was performed,
>Omentum was left in, although a number of biopsies were taken. Liver
>function tests are normal. I am 43.
>
>Now, CA-125 is STILL elevated (90). Current plan to to repeat CT scans
>and CA-125 in 8 weeks. What else should I consider.
--
Harvey S. Marchbein, M.D. FACOG, FACS
Great Neck, New York
**Note: Opinions expressed here are for educational purposes only
and, as such, do not constitute a physician-patient relationship.
This information is not intended to supplant the need for you to
consult with your physician prior to choosing therapeutic options
and/or interventions.
**Private emails cannot be entertained due to time constraints,
consequently no private emails will receive a response.
**Thank you for your understanding.
Please be aware that all e-mail on this forum is archived and can be viewed at
http://forums.obgyn.net/womens-health,
http://forums.obgyn.net/pregnancy-birth or
http://forums.obgyn.net/young-women
and is accessible to anybody on the
internet including internet search engines. This should be taken into
consideration before sending postings of a personal or confidential nature.
![[ Women's Health Forum ]](http://www.obgyn.net/images_women/wh-forum.gif)