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Re: Fibroids, Polyps, Uterine Bleeding, Depo and Premarin

From: Harvey S. Marchbein, M.D. (anonymous@obgyn.net)
Sun, 30 Dec 2001 18:53:58 -0600 (CST)


Looks like unrelated to the DepoProvera, you have fibroid(s) and possibly polyps. Neither of these should be responsive to progesterone (DepoProvera). I have no idea what ?prosterin? is so cannot comment on that. With the abnormal bleeding so common with Depo, it can frustrate the patient and the doctor. Sometimes, the only way to counteract the exaggerated effects of the Depo is to add estrogen such as Premarin, to even out the unbalanced effect of just one hormone.

Hope this helps and write back anytime for more information.

Dr. M

At Sun, 30 Dec 2001, Bess wrote: >
>I'm 43 and have virtually bled continously, since starting depo-provera
>a year ago. I've had ruptured ovarian cysts and emergency surgery for
>excessive bleeding/fibroids previously. An ultrasound found a 1/2"
>fibroid pushing the wall out and an endo biopsy found indications of
>polyps plus the lining contained prosterin (?) (from the depo I'm
>assuming). There is tenderness, moderate discomfort and occasionly
>sharp pains at the top of the uterus. I've been prescribed Premarin
>1.25 to take for 10 days to control the bleeding. I'm in good health
>other than very high choloestrol. With both a fibroid, possible polyps
>and a 'history', why hormone replacement?
>
>I've looked all over the web for information and it just makes me more
>confused. My Dr., before and after the endo biopsy, determined the sole
>cause to be Depo-Provera and whether it's her explanation or me 'being
>dumb' - I just don't understand all of this.
>
>--
>Thank you any help is making me comfortable with this.
>

--
Harvey S. Marchbein, M.D. FACOG, FACS
Great Neck, New York

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