WOMENS-HEALTH Messages for May, 2001: Re: Acetaminophen and BCP

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Re: Acetaminophen and BCP
From: William McIntosh, MD (anonymous@obgyn.net)
Tue, 15 May 2001 11:39:03 -0500 (CDT)

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In reply to: M: "Acetaminophen and BCP"

At Tue, 15 May 2001, M wrote: >
>While I was on my placebo pills of my BCP's, I took cold medicine that
>had a lot of acetaminophen in it. I then read on my package information
>that acetaminophen may increase plasma ethinyl estradiol concentrations
>possibly by inhibition of conjujation.
>What does this mean?
>
>Would this have any effect on effectiveness of my pill?
>
>Thanks

In actually practice, no it will not have an effect on the effectiveness of your pill. The theoretical concern is that the since tylenol and the hormones in the pill are metabolized in the same liver pathways, that having the two of them together could cause there to be a delay in that metabolism. If that were to occur, it would actually make your pill more effective as the estrogen levels would be slightly higher. In reality, a normal liver is more than capable of dealing with minor issue.

-- William D. McIntosh, MD, FACOG
This is for educational purposes only, and is not a substitute for consultation and examination by a licensed medical professional.

Next message: Janice: "Patient's Rights"
Previous message: William McIntosh, MD: "Re: Pelvic Exams During Late Pregnacy"
In reply to: M: "Acetaminophen and BCP"

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