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Re: anticardiolipin antibodies

From: M. Kelly Shanahan, MD, (anonymous@obgyn.net)
Sat, 31 Mar 2001 00:26:55 -0600 (CST)


At Fri, 30 Mar 2001, anonymous wrote: >
>I left this message earlier, but doesnt' seem to have posted. If this
>is a repeat please everyone accept my apologies.
>
>Trying to understand the results of my tests and what would be an
>appropriate course of action. In Jan and Feb conceived. Positive
>pregnancy tests, but both times period started. My doctor tested me for
>antibodies. The results are as follows. ANA Neg. ACL IGA 7 Gpl. IGM
>19 MPL (test result reads HIGH) IGA <6 APL. For the lupus anticoagulant
>the PTT-LA is 38.9 seconds and the Dilute Russell's is 25.7 (Test result
>reads it as being LOW)
>
>I understand that it is a positive result for ACL IGM. But is this way
>high out of normal range. I've found different info on line from low
>positive to inconclusive. I think the lupus is in the normal to low
>normal range. Correct?

yes -- and the ranges may vary a bit from lab to lab >
>I have gotten conflicting opinions from two doctors. ONe says he would
>treat with baby aspirin and heparin for the next pregnancy and the other
>said these were insignificant results and wouldn't treat at all. Any
>viewpoint?

well, I'll tell you my results were pretty similar to yours, but it was my APL IgA that was borderline. I got the same conflicting advice (and I'm an ob-gyn!!) I chose to do the aspirin and heparin with my next injectable/IUI cycle (I had trouble getting pregnant too). I gave myself heparin shots twice a day for 37 weeks, and took a baby aspirin daily. My 2 year 4 month old daughter is sleeping peacefully in hte next room. Needless to say, I'm a big believer in aspirin/heparin, and I know my personal exerience clouds my judgement in this matter. Heparin does have risks, including osteoporosis, but I'll give my left (or right - or both) hip for the privalege of having my daughter. >
>Don't know if this is significant or not, but I'm in my late 30s and
>have had one child three years ago. Sorry for the long post.
>Many thanks for your helpful advice and your time.
>
>--
>Anonymous
>

--
M. Kelly Shanahan, MD, FACOG
South Lake Tahoe, CA

author, Your Over-35 Week-by-Week Pregnancy Guide

****Responses are for educational purposes only and do not construe a doctor-patient relationship. This does not replace a face-to-face consultation with your own doctor.****

***Private e-mails will NOT be answered***






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