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Re: Tests for ovarian cancer

From: R. Daniel Braun, MD (anonymous@obgyn.net)
Sat, 30 Sep 2000 08:19:38 -0500 (CDT)


At Fri, 29 Sep 2000, dahlia wrote: >
>Is the new blood test for ovarian cancer more sensitive than the
>intravaginal ultrasound. Does it diagnose early enough to affect
>outcome, which I understand that the ultrasound does not.

All of hte tests for ovarian cancer available so far, including transvaginal ultrasound on an annual basis, have the problem of having an extremely high number of False Positive tests. This means that a large number of women who have nothing wrong with their ovaries end up having major surgery when they didn't need it. Most of the tests also have false negatives. So far none of them are acceptable for use as a screening test. Some of them are helpful in other ways. Ca-125 is good to follow the treatment of ovarian cancer. IOW, if a woman has ovarian cancer, we draw a Ca-125 on the first day after her surgery. If the Ca-125 is elevated then we can use this as a marker for her ovarian cancer. If it goes to zero, we will have seemed ot have gotten the cancer. If it then later starts to go up we know the cancer is coming back. Many women with elevated Ca-125 do not have ovarian cancer.

RDB

--
R. Daniel Braun, MD FACOG  FOG

This is for educational purposes only, and is not intended to be replacement or substitute for consultation and examination by an appropriate medical professional. Due to time constraints, private e-mails cannot be answered.






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