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Re: Taking Bactrim DS while pregnant From: R. Daniel Braun, MD (anonymous@obgyn.net) Thu, 8 Jun 2000 21:21:54 -0500 (CDT) Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: R. Daniel Braun, MD: "Re: High temps and pregnancy" Previous message: R. Daniel Braun, MD: "Re: Question about miscarriages" In reply to: Lisa: "Taking Bactrim DS while pregnant" At Thu, 8 Jun 2000, Lisa wrote: > >I am beginning my 12th week of pregnancy...My OB/GYN prescribed Bactrim >DS(pharmacy filled it generically) for an e-coli vaginal infection...I >have read some disconcerning info on taking the drug while >pregnant...All input would be appreciated. > >Lisa > >-- >Lisa Wank > While Bactrim has never been shown to cause birth defects, the two agents in it Sulfa and trimethoprim are both antimetabolites. We don't like to give antimetabolites to pregnant women just because the class of drugs as a whole seems to do some bad things. IOW, there is no evidence that it does harm, but we still worry a little on theoretical grounds. I am unfamiliar with an E. coli infection of the vagina in postmenarchal, premenopausal women. I also don't think that bactrim would have high enough levels in the vagina to do anything. It has high levels in the urine, but not the vagina. RDB -- R. Daniel Braun, MD FACOG FOG This is for educational purposes only, and is not intended to be replacement or substitute for consultation and examination by an appropriate medical professional. Due to time constraints, private e-mails cannot be answered. Next message: R. Daniel Braun, MD: "Re: High temps and pregnancy" Previous message: R. Daniel Braun, MD: "Re: Question about miscarriages" In reply to: Lisa: "Taking Bactrim DS while pregnant"

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