WOMENS-HEALTH Messages for April, 2000: Re: gender selection

Re: gender selection

From: anonymous (anonymous@obgyn.net)
Wed, 12 Apr 2000 10:35:39 -0500 (CDT)

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At Wed, 21 Jan 1998, Nina wrote: >
>At Wed, 16 Jul 1997, Laurie wrote:
>>
>>At Wed, 16 Jul 1997, Thomas wrote:
>>>
>>>At 10:14 AM 7/16/97 -0500, you wrote:
>>>>My husband and I have three girls and will be trying for baby number
>>>>four in the next year. We are seriously considering sperm seperation to
>>>>try to achieve a boy. Are there any other ways we could
>>>>achieve our goal? What do you think of sperm seperation?
>>>>
>>>If I may add to this, we have two boys and are in the same "boat". We want
>>>another baby and would love to have a girl, but either will be great. What
>>>about the Shettles Method?
>>>
>>>Jeff and Beth Harrell
>>>
>>>Beaching, Fishing,
>>>NASCAR Racing and
>>>Homeschooling in NC
>>
>>Our embryologist just reviewed this topic for us at my request. Here
>>are some of the studies he discussed:
>>
>>In a 1970 paper, Shettles claimed that sexual position, female orgasm,
>>vaginal pH, depth of penetration, and timing related to ovulation
>>affected the sex of the baby. He also reported that morphological
>>differences exist between "male" (Y-bearing) and "female" (X-bearing)
>>sperm. These findings have not been replicated. There are several
>>conflicting studies on timing of ovulation and sex of the baby, and more
>>sophisticated microscopic techniques have failed to find morphologic
>>differences in the sperm.
>>
>>Some studies have shown that (a) the use of Clomid and (b) cycles with a
>>longer follicular phase (which would be expected in Clomid cycles) have
>>a higher incidence of female births. Of course, other studies have
>>shown no difference.
>>
>>Ericcson in 1973 published an albumin separation method reported to
>>isolate Y-bearing sperm. He subsequently patented the method and it is
>>in commericial use. Several studies have since shown that use of this
>>method does not affect the sex ratio.
>>
>>Flow cytometry, another lab technique which involves staining and then
>>sorting the sperm, has been shown to affect the sex ratio. The problems
>>with this technique are (1) does the staining affect the subsequent baby
>>in any way and (2) sperm recovery is very limited, to the point of
>>requiring assisted reproductive techniques such as IVF/ICSI to achieve
>>pregnancy.
>>
>>Pre-implantation biopsy of embryos is also being more widely performed
>>(usually to prevent transmission of genetic conditions which affect
>>males vs. females), but it has the disadvantages of requiring IVF and
>>of risking the loss of the embryo.
>>
>>So what this boils down to is there's not a reliable, inexpensive method
>>for sex selection--and I wonder if that's all bad :-)
>>
>>--
>>Laurie Lovely, MD
>>RE fellow, UNC-Chapel Hill
>>
>--
>Hello Laurie,
>
>My husband and I have been doing some research and ran across your comments on the Ericcson 1973 study on albumin separation to isolate Y-bearing sperm. The clinic we have contacted claim hit rates of up to 75% for childs sex preselection. Would you be so kind as to pass on any of the references you mentioned citing poor success rates for this method ? I would like to have the clinic explain/refute those results. Many thanks.
>
>Nina B.
>

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