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Re: PAP/Colpo biopsy discrepancy and clarification of CIN progression

From: Madeline (anonymous@obgyn.net)
Wed, 26 Jan 2000 14:41:44 -0600 (CST)


Hi Shannon

I am trying to find information about LGSIL, because my Dr.just told me my pap resulted in this. Where can I get more information about it? do you know? thanks Madeline in Philadelphia and Boston. At Mon, 1 Mar 1999, Shannon wrote: >
>Hi. Here's my brief history. I'm 29, have three children and started
>having ASCUS about 1 1/2 years ago (with a normal pap in the middle) and
>through one pregnancy. I had a colposcopy and ECC done 7 months ago
>(5/98). There was nothing to biopsy and my ECC was negative.
>
>I had a follow up pap 7 months later (12/98)-results were LGSIL
>suggestive of HPV involvement. I had another colposcopy, ECC and pap
>done (1/99). Three biopsies were taken: LGSIL, HPV and
>atypia/inflammation. My ECC was negative and my pap showed moderate
>dysplasia.
>
>So, they had a conference and decided that my pap and biopsies did in
>fact match and gave me the opportunity to either "wait and see" or LEEP.
>I picked the LEEP and will have that done in a couple weeks (3/99).
>
>I am concerned that this is faster moving than the literature says. Less
>than a year ago, I had nothing to biopsy on colpo and now I have
>moderate dysplasia. Could I have cancer? The doctors will never flat
>out say "no, of course not". But, really, everything I've read says
>that CIN starts out at the basement membrane and works up to the top and
>only then proceeds to invade the basement membrane and become invasive.
>So, if I don't have anything more than moderate dysplasia on PAP (with
>my biopsy being LGSIL), what are my odds of having cancer?
>
>Also, should I feel comfortable having this LEEP done by a PGY2
>resident? I am a little worried that he won't get the entire lesion and
>really would prefer someone with more experience.
>
>Thank you!




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