Re: Agenesis of the corpus callosum and mid sagittal views of the fetal brain

From: Paula S. Woletz, RDMS, RDCS, MPH (woletzps@umdnj.edu)
Wed Sep 8 18:16:16 1999


We don't routinely screen for agenesis of the corpus callosum, but when there is the suspicion (or a significant history), we've been using the mid sagittal views with a great deal of success. It's not always obtainable, but sometimes with a vertex presentation, transvaginal scans work well. We augment the 2D image with the use of color flow and color power Doppler. In cases of ACC, we've noted the absence of the pericallosal artery. (Which raises the question of whether the corpus callosum fails to develop because of abnormal vasculature or whether the development of the pericallosal artery is affected by ACC--which comes first, the chicken or the egg?) We've begun a study to see how early we can see the corpus callosum on mid sagittal scans, and which is visualized earlier, the corpus callosum on gray scale or the pericallosal artery on color Doppler. I don't have information on the incidence of colpocephaly associated with ACC, but the finding of colpocephaly (as well as Dandy Walker malformations and variants) is often what makes us look for ACC in the first place.

I hope this is helpful.

Regards, Paula

At Wed, 8 Sep 1999, philippe.coquel wrote: >
>Agenesis of the corpus callosum: Role of mid sagittal views of fetal brain ?
>
>1) What do you think of the systematic use of the mid sagittal views in the screening of agenesis of the corpus callosum?
>
>2) In your experience, are these views always possible, useful and of good quality ?
>
>3) In a recent French series of 165 cases, colpocephaly is absent in 25 % of the complete agenesis and in 33% of partial agenesis. I don't' find similar features in others series or publications. Have somebody a similar experience?
>
>Thanks for your answers
>
>Ph Coquel, MD
>
>74960 Cran Gevrier
>
>France

--
Paula S. Woletz, RDMS, RDCS, MPH
University of Medicine and Dentistry of New Jersey/
St. Peter's University Hospital
New Brunswick, NJ
woletzps@umdnj.edu



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