Re: microcephaly

From: Dr. Ross Welch (rwelch@liv.ac.uk)
Wed May 12 11:16:53 1999


Your not suggesting that fetal microcephaly does not exist without ventriculomegaly? I have seen several cases of pathologic and nonpathologic microcephaly without ventriculomegaly.

Dear all

I echo Wayne's position. There are many recognised syndromes and genetic diseases with microcephally but no ventriculomegally....the problem is when to label the small head "microcephalic" Experience suggests that it is not usually possible until well into the third trimester unless there is previous pregnancy data to go on.

This issue raised however was how do we differentiate between inaccurate measurement due to head engagement and microcephally. The answer has to be that we cannot. If the head is engaged then we should not attempt to measure the BPD/HC and state why.

Ross

--
Ross Welch
Consultant in Fetomaternal medicine
Duchess of Westminster Wing
Arrowe Park Hospital
Upton, Wirral.
UK

Current president International Fetal Medicine and Surgery Society.




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