Re: Isoimmunization

From: James S Smeltzer MD (gaperina@mindspring.com)
Thu Mar 11 05:03:23 1999


Dear NT,

The risk is about 1/1000 for anti D BIG D - there is no little d -, and the RhIG does NOT protect against developing anti big or little C / c. At these titers, needs to be followed in second half of pregnancy by perinatologist and does NOT need RhIG if she has Anti BIG D. JSS

At 08:10 PM 3/10/1999 -0600, you wrote: >Need suggestions with how to manage the following case. 37 yo wf
>presented with c (1:32) and d (1:64) antigens s/p termination of 10 week
>pregnancy due to no fetal heartbeat. G2 P1. Rhogam administered at 28
>weeks and postpartum. Non remarkable labs prior to miscarriage. Have
>you ever seen a case where rhogam was given and still developed c and d
>antibodies? What has been your experience with cases where next
>pregnancy fetus has positive antibodies? Thanks.
>
>NTPIERCE@aug.com
>




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