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Re: Ultrasound markers of fetal anemiaFrom: Dr. Ross Welch (rwelch@liv.ac.uk)Wed Jan 20 17:19:27 1999
ultrasound markers of fetal anemia. Dear Matias I have spent my years of post doc research looking at non invasive ways of detecting fetal anaemia and have published several times on the issue. There is no doubt that fetal hct and fetal blood viscosity are related (in a log relationship). I can show you the effect of decreased viscosity on virtually any vessel's flow velocity waveform but I can't measure it!! The state of the art must therefore be as James has replied, the only sure way is to look for hydrops, but if you look around the kidneys and at the entrance of the cord into the abdomen you will see it very early. Kypros Nicolaides published that hydrops only happens when the fetal hb is 7g/dl below the mean for gestation so it does not happen till a hb of ~3g/dl (hct 10% or lower) in early disease. Alastair Roberts from New Zealand has published some useful graphs of liver length as a predictor but they are operator dependant.
-- Ross Welch Consultant in Fetomaternal medicine Duchess of Westminster Wing Arrowe Park Hospital Upton, Wirral. UK
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