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I: yolk sac and early pregnancyFrom: Andrea Corda (acord@tin.it)Fri Jan 15 12:19:26 1999
Messaggio a pił sezioni in formato MIME. -----Messaggio originale----- Da: Andrea Corda <acord@tin.it> A: lyonsea@email.msn.com <lyonsea@email.msn.com> Data: venerdì 15 gennaio 1999 20.04 Oggetto: yolk sac and early pregnancy Got a number of cases concerning abnormal size and growth of yolk sac and early pregnancy failure,namely:abnormal yolk sac growth from the very early days (i.e. since its first identification via TV scans).This means,for example,that if I measure a CRL of 4 mm in a viable embryo I should find a similar diameter of the yolk up to the size (mean) of 5 mm ,when the embryo goes on growing and the yolk sac remains more or less of the same size.If I find a yolk sac diameter of,say,7 mm and a CRL of 4 in a viable pregnancy,there are two possibilities:1)spontaneous abortion in a few weeks or days or 2) a subsequent chromosomal abnormality detected either via CVS (abnormal nuchal fold) or amniocentesis.Up to now I've collected a number of trisomies (21,18,13,15 and 22 ,Klinefelter)and monosomies (Turner) using this simple rule (you can use it as a rule of thumb:in the early phase of every pregnancy yolk sac and embryo grow together with the same rate up to the size of 5 mm;if the yolk sac grows at a faster rate then something wrong is happening.Also the heartbeat can give you some clue along with the proportions between yolk sac ,gestational sac and embryo,but this has more to do with other illnesses (ex:diabetes).I intend to publish these data;it took me four years to collect them and obtain the cytogenetic analysis either on fresh abortive material or CVS or amnio (depending on how far the pregnancy was gone).This is not a simple task down here in Sardinia!Please reply via E-mail Dr.Andrea Corda ,Cagliari,Sardinia,Italy E-mail acord@tin.it
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