Re: your opinion

From: Terry DuBose (terrydubose@sbcglobal.net)
Sun Jul 8 11:11:38 2007


Dr. Mohile

Your case has certainly revived discussion on this list. Very interesting.

http://www.obgyn.net/ultrasound/?page=/ultrasound/present/0707/pregnancy_mole

Many have offered opinions, and some have asked for more images and other results. http://forums.obgyn.net/ultrasound/index.html#archives

We hope this has been helpful. Any follow-up will be welcome.

Thanks, Terry J DuBose

James Smeltzer <James.Smeltzer@wellstar.org> wrote: The vascularity of the uterus can be found with contraction after a SAb - as I saw in a case today. It has been found with a cornual mole once by me. It DOES suggest the possibility of a vascular neoplasm but I do not think it is the neoplasm itself, although I have limited experience with locally invasive moles of the uterus.

- as apparently do others. See this rather thin list of ovid refs for ultrasound and invasive mole:

I have also asked for jumps to relevant images to help sort this out. In conclusion I do NOT believe that molar tissue is proven in this case. HCG levels should be at their apex and falling soon. This would be the way I followed this case, as well as by US, of course.

Asymmetric fetal SGA would be a sign for partial mole, as pointed out already. These almost never are invasive or metastatic. I would be surprised if this were one. Her history is VERY interesting and needs more elaboration.

Thanks Jim S

Ultrasound in Obstetrics and Gynecology Volume 3 Issue 1 Page 51-53, January 1993

To cite this article: M. T Chau, F. Y Ghan, T. C Pun, L Leong (1993) Perforation of the uterus by an invasive mole using color Doppler ultrasound: case report Ultrasound in Obstetrics and Gynecology 3 (1), 51–53. doi:10.1046/j.1469-0705.1993.03010051.x

1. Jain, Kiran A MD Gestational Trophoblastic Disease: Pictorial Review. Ultrasound Quarterly. 21(4):245-253, December 2005. |
2. Dogra, Vikram MD *; Paspulati, Raj Mohan MD +; Bhatt, Shweta MD ++ First Trimester Bleeding Evaluation. Ultrasound Quarterly. 21(2):69-85, June 2005.

3. Hui, Pei MD, PhD *; Martel, Maritza MD *; Parkash, Vinita MD + Gestational Trophoblastic Diseases: Recent Advances in Histopathologic Diagnosis and Related Genetic Aspects. Advances in Anatomic Pathology. 12(3):116-125, May 2005. |
4. SOPER, JOHN T. MD Staging and Evaluation of Gestational Trophoblastic Disease. Clinical Obstetrics & Gynecology. 46(3):570-578, September 2003. |
5. SMITH, HARRIET O. MD Gestational Trophoblastic Disease Epidemiology and Trends. Clinical Obstetrics & Gynecology. 46(3):541-556, September 2003. |
6. MERNAGH, JOHN R. M.D., PH.D., F.R.C.P.C. *; CACO, CHRISTOPHER M.D., F.R.C.P.C. *; MOHIDE, PATRICK M.D., F.R.C.S.C. +; POW-HERRITY, TRACY R.D.M.S. * Ultrasound Assessment of Fetal Neoplasia. Radiologist. 10(3):109-119, May 2003. |
7. Genest, David R. M.D. Partial Hydatidiform Mole: Clinicopathological Features, Differential Diagnosis, Ploidy and Molecular Studies, and Gold Standards for Diagnosis. International Journal of Gynecological Pathology. 20(4):315-322, October 2001. |
8. PREIDLER, KLAUS W. MD *; LUSCHIN, GERO MD +; TAMUSSINO, KARL MD +; SZOLAR, DIETER M. MD *; STISKAL, MICHAEL MD ++; EBNER, FRANZ MD * Magnetic Resonance Imaging in Patients with Gestational Trophoblastic Disease. Investigative Radiology. 31(8):492-496, August 1996.

James S. Smeltzer, MD, FACOG, SMFM Consultant, Maternal Fetal Medicine Wellstar Physicians' Group Northwest Women's Care 787 Campbell Hill St Marietta GA 30060 James.Smeltzer@wellstar.org VM 678-290-3035 Off 770-528-0260 Page 404-318-3451




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