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Re: Informal poll on trisomy 21 screening From: Dave Berck (djberck@yahoo.com) Mon May 16 08:34:46 2005 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: James Smeltzer: "Informal poll on trisomy 21 screening" Previous message: art fougner, md: "Re: Informal poll on trisomy 21 screening" Maybe in reply to: James Smeltzer: "Informal poll on trisomy 21 screening" Next in thread: Latha Natarajan: "Re: Informal poll on trisomy 21 screening" I have also had a false negative similar to yours. I also had a patient who screened positive on 1st tri screening, then declined amnio. Then had a 2nd tri serum screen which was negative, then had markers on "genetic" sono at 20 weeks at which point she decided to have amnio which revealed tri-21. Since these are all screening tests, one would expect false positives and negatives. That's why I do the "community standard" (2nd tri multiple marker screening), and try to counsel people sensibly when it is positive after a negative 1st tri screen, which happens frequently. --- "art fougner, md" <evsono@pipeline.com> wrote: > Early screen with NT, Free Beta HCG, PAPP-A, and > Maternal Age. A > cautionary tale - have already had one False > Negative - 27 y/o who had > low risk 1st TM screen had 2nd TM serum screen > performed by her OB read > as high risk for Down's. After counseling, the > patient elected > amniocentesis at which time Trisomy 21 was > discovered. As Yogi Berra so > aptly put it, "It ain't over til it's over." > > Art > > At Sat, 14 May 2005, Dave Berck wrote: > > > >What's your approach to trisomy 21 screening? > > > >1st tri screening with NT and 1st tri screening? If > >so, which serum tests? free beta and papp-A > > > >AFP3 / AFP4 / AFPMore? > > > >"Genetic scan"? > > > >I'm interested to hear your opinion. > > > >-- > >Dave Berck, MD, MPH > > > >David J. Berck, MD, MPH > > > > -- > art fougner, md > > "If you don't know where you are going, you will > wind up somewhere else." > Lawrence Peter Berra > David J. Berck, MD, MPH Next message: James Smeltzer: "Informal poll on trisomy 21 screening" Previous message: art fougner, md: "Re: Informal poll on trisomy 21 screening" Maybe in reply to: James Smeltzer: "Informal poll on trisomy 21 screening" Next in thread: Latha Natarajan: "Re: Informal poll on trisomy 21 screening"

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