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EIF and CPCFrom: art fougner, md (evsono@pipeline.com)Tue Apr 27 11:35:07 2004
In the April issue of JUM, Drs. FIlly, Benacerraf, Nyberg, and Hobbins have published an editorial concerning the EIF and CPC as "soft markers" for aneuploidy. They offer a possible solution to the dilemma of reportage and suggest the following suggestion: "A (CPC or EIF) is identified. Although this finding has been reported in association with fetal chromosome abnormalities, no other major or minor anomalies were identified in this fetus. In the absence of other risk factors, this is considered a normal variant, and no further evaluation is recommended." They further suggest: "The attending obstetrician is notified so that the risk status of the patient can be ascertained. (In many clinical situations, the attending obstetrician may be the individual who performed the sonography and recognized the CPC or EIF. As well, the sonologist may be a maternal-fetal medicine consultant who could then make the final determination regarding the patient’s risk status.)" There is one caveat - if circumstances preclude obtaining sufficient views of the fetal anatomy, the above may not apply. I would suggest all who peruse this forum to read this editorial as well as the article: Claudio Coco, Philippe Jeanty, and Cerine Jeanty An Isolated Echogenic Heart Focus Is Not an Indication for Amniocentesis in 12,672 Unselected Patients J Ultrasound Med 2004 23: 489-496. which appears in the same issue. art
-- art fougner, md ich bin ein New Yorker
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