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Re: conjoined twinsFrom: Serge Guichard (sguich@transnethaiti.com)Wed Feb 11 06:57:30 2004
1rst Hypothesis: The 2 fetus are female and in one of them develops a secreting tumor(Androblastoma,adrenal tumor ...) producing testosterone responsible for the masculinisation of the external genitalia.The problem is:the effect of those mal hormones should affect both fetus because of the intercommunication of the placental vessels. 2nd Hypothesis: The embryo at the origin is male and during the spilt of the zygote there may have some accident during the mitose resulting in some deletion of the Y chromosome.On the Y chromosome there are some genes inducing the developement toward the male sex organs.If those gene are missing the gender develops spontaneously to female.So one twin stay with male organes and the other with the sex chromosome disorder looks like a female.
-- Serge Guichard,MD
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