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Re: Early Cardiac Function Predicts Miscarriage RiskFrom: Terry J DuBose (tjdubose@juno.com)Thu Dec 4 17:00:29 2003
This message is in MIME format. Since your mail reader does not understand this format, some or all of this message may not be legible. ----__JNP_000_2e2d.11ee.491b Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: 8bit For some reason I can no longer respond to messages from my office... had to forward this response home and send from there. Terry ------------------------------------------ Art, I saw this,... it is very interesting. The bit about lack of ------------------------------------------ oxygen in the embryonic period is new, I think: ------------------------------------------ "The cause of embryonic congestive heart failure – not enough oxygen reaching the heart – is much the same in embryos as it is in the elderly," Dr. Birnholz said. "I suspect that if the blood vessels that feed the placenta do not properly form or are slightly delayed in development, the heart does not get the support required." Because the embryonic heart rate (EHR) acceleration and deceleration curve has the shape of a classic “damping feedback curve” ( see: http://www.obgyn.net/us/cotm/0001/ehr2000b.htm ), we have always thought that there were probably 3 or more variables that control the shape of the curve. In addition, because the curve peaks (9.2 LMP weeks) at about the same time as the hCG and when the ventricular septum closes, we assumed that the variables may include electrical (bundle of His & 2 branches completion), hydraulic (VS closure), or hormonal (hCG curve), but did not consider the oxygen. Of course, the oxygen might influence one or more of the variables, including normal ventricular closure or other development. I will be anxious to see the published research… both for the new information, as well as to see if our work will be referenced. DuBose TJ, Cunyus JA, Johnson LF; Embryonic Heart Rate and Age; J of Diagnostic Medical Sonography; 6:151-157, 1990, May/June Peace, Terry J. DuBose, M.S., RDMS Little Rock, Arkansas USA At Wed, 3 Dec 2003, art fougner, md wrote: Radiological Society of North America 03.12.2003 Doppler ultrasound predicts risk of miscarriage Doppler ultrasound performed in early pregnancy can accurately identify embryonic congestive heart failure and subsequent risk of miscarriage, according to research being presented today at the 89th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA). "The chances the pregnancy will continue are very high, about 95 percent, when Doppler ultrasound confirms normal embryonic heart function at six weeks," said the study’s author Jason C. Birnholz, M.D., president of Diagnostic Ultrasound Consultants in Oak Brook, Ill. "Over 99 percent of pregnancies with an abnormal Doppler pattern do not continue." The Doppler test measures the speed of red blood cells moving through vessels to determine pressure dynamics within the embryo’s heart. Terry J. DuBose, M.S., RDMS, FSDMS, FAIUM Assistant Professor & Director, Diagnostic Medical Sonography Program University of Arkansas for Medical Sciences, CHRP 4301 West Markham St. Mail Slot #563 Little Rock, Arkansas, 72205 USA 501-686-6510 DuBoseTerryJ@UAMS.edu http://www.io.com/~dubose/ http://www.uams.edu/chrp/dms/default.asp http://www.obgyn.net/us/panel/panel.htm ----__JNP_000_2e2d.11ee.491b Content-Type: text/html; charset=iso-8859-1 Content-Transfer-Encoding: quoted-printable <!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN"> For some reason I can no longer respond to messages from my office...
had
to forward this response home and send from there. Terry ------------------------------------------ Art, I saw this,... it is very=20 ------------------------------------------ Art, I saw this,... it isinteresting. The bit about lack of oxygen in the embryonic = ------------------------------------------ Art, I saw this,... it isperiod is new, I think: "The cause of embryonic congestive heart failure – not enough oxygen reaching the heart – is much the same in embryos as it is in the elderly," Dr. Birnholz said. "I suspect that if the blood vessels that feed the placenta do not properly form or are slightly delayed in development, the heart does not get the support required." Because the embryonic heart rate (EHR) acceleration and deceleration curve has the shape of a classic “damping feedback curve” ( see: http://www.obgyn.net/us/cotm/0001/ehr2000b.htm ), we have always thought that there were probably 3 or more variables that control the shape of the curve. In addition, because the curve peaks (9.2 LMP weeks) at about the same time as the hCG and when the ventricular septum closes, we assumed that the variables may include electrical (bundle of His & 2 branches completion), hydraulic (VS closure), or hormonal (hCG curve), but did not consider the oxygen. Of course, the oxygen might influence one or more of the variables, including normal ventricular closure or other development. I will be anxious to see the published research… both for the new information, as well as to see if our work will be referenced. DuBose TJ, Cunyus JA,
Johnson LF; Embryonic Heart Rate and Age; J of Diagnostic Medical Sonography;
6:151-157, 1990, May/June
----__JNP_000_2e2d.11ee.491b--
Peace, Terry J. DuBose, M.S., RDMS Little Rock, Arkansas USA At Wed, 3 Dec 2003, art fougner, md wrote: Radiological Society of North America 03.12.2003 Doppler ultrasound predicts risk of miscarriage Doppler ultrasound performed in early pregnancy can accurately identify embryonic congestive heart failure and subsequent risk of miscarriage, according to research being presented today at the 89th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA). "The chances the pregnancy will continue are very high, about 95 percent, when Doppler ultrasound confirms normal embryonic heart function at six weeks," said the study’s author Jason C. Birnholz, M.D., president of Diagnostic Ultrasound Consultants in Oak Brook, Ill. "Over 99 percent of pregnancies with an abnormal Doppler pattern do not continue." The Doppler test measures the speed of red blood cells moving through vessels to determine pressure dynamics within the embryo’s heart. Terry J. DuBose, M.S., RDMS, FSDMS, FAIUM Assistant Professor & Director, Diagnostic Medical Sonography Program University of Arkansas for Medical Sciences, CHRP 4301 West Markham St. Mail Slot #563 Little Rock, Arkansas, 72205 USA 501-686-6510 DuBoseTerryJ@UAMS.edu http://www.io.com/~dubose/ http://www.uams.edu/chrp/dms/default.asp http://www.obgyn.net/us/panel/panel.htm
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