Re: Soft markers for genetic problems

From: Allen Worrall (jworrall@alaska.net)
Mon Oct 13 10:52:48 2003


I am pretty sure that nuchal translucency and nuchal fold have the highest likelihood ratio.

Allen

>----- Original Message -----
From: "Terry J. DuBose" <duboseterryj@uams.edu> To: "Multiple recipients of list ULTRASOUND" <ultrasound@dns.obgyn.net> Sent: Monday, October 13, 2003 7:44 AM Subject: Re: Soft markers for genetic problems

> Ok, Ok,... I am primarily interested in the relative benefit (ranking) of
the various soft markers, higher to lower... it is an academic question, not a clinical one. Thanks, Terry >
> ultrasound@obgyn.net writes:
> >What matters is not the PPV, but also the confidence interval (is a RR of
3 > >significant ? is 1/139 different from 1/289 ?)
> >
> >-----Original Message-----
> >From: ultrasound@obgyn.net [mailto:ultrasound@obgyn.net] On Behalf Of
Terry > >J. DuBose
> >Sent: Monday, October 13, 2003 8:46 AM
> >To: Multiple recipients of list ULTRASOUND
> >Subject: Soft markers for genetic problems
> >
> >Does anyone here have a recent reference that gives the accuracy
(positive > >predictive value) of "soft markers" in obstetrical sonography?
Particularly > >for those below and/or others? thanks Terry
> >
> >Long bone length
> >Nuchal translucency
> >Ear length
> >Bowel
> >Pelvic bone width
> >Heart/intracardiac foci
> >Toes/sandal foot
> > hands/missing middle metacarpal fifth digit
> >Pylectasis
> >3 vessel cord
> >Choroid plexus cysts
> >Nasal bones
> >
> >Terry J. DuBose, M.S., RDMS, FSDMS, FAIUM
> >Assistant Professor & Director, Diagnostic Medical Sonography Program
> >University of Arkansas for Medical Sciences, CHRP
> >4301 West Markham St. Mail Slot #563
> >Little Rock, Arkansas, 72205 USA
> >501-686-6510
> >DuBoseTerryJ@UAMS.edu
> >http://www.io.com/~dubose/
> >http://www.uams.edu/chrp/dms/default.asp
> >http://www.obgyn.net/us/panel/panel.htm
> >
>
> Terry J. DuBose, M.S., RDMS, FSDMS, FAIUM
> Assistant Professor & Director, Diagnostic Medical Sonography Program
> University of Arkansas for Medical Sciences, CHRP
> 4301 West Markham St. Mail Slot #563
> Little Rock, Arkansas, 72205 USA
> 501-686-6510
> DuBoseTerryJ@UAMS.edu
> http://www.io.com/~dubose/
> http://www.uams.edu/chrp/dms/default.asp
> http://www.obgyn.net/us/panel/panel.htm
>




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