ULTRASOUND Messages for December, 2002: Re: risk for down syndrome

Re: risk for down syndrome
From: Patrizia (pellpatri@iol.it)
Wed Dec 4 14:47:05 2002

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the MOM for free beta was 2,17 and for papp was 2,0 bye
>----- Original Message -----
From: "Dave Berck" <djberck@yahoo.com> To: "Multiple recipients of list ULTRASOUND" <ultrasound@mail.medispecialty.com> Sent: Tuesday, December 03, 2002 8:24 PM Subject: Re: risk for down syndrome
> I would need the MOMs for the free beta and papp-A.
>
> --- Patrizia <pellpatri@iol.it> wrote:
> > I tired to calculate the risk by myself but I fail
> > could you please show me how you calculate the
> > sequential risk in detail,
> > using the number I gave:
> > risk for maternal age 1:411
> > risk for NT - FreeBHCG - Papp-a - maternal age
> > 1:3212
> > risk for tri test 1:381
> > thank you again
> > patrizia

>> > ----- Original Message -----
> > From: "R L Meisel" <rmeisel@mac.com>
> > To: "Multiple recipients of list ULTRASOUND"
> > <ultrasound@mail.medispecialty.com>
> > Sent: Saturday, November 30, 2002 2:35 AM
> > Subject: Re: risk for down syndrome
> >
> > > >le 29/11/02 9:22, Patrizia :
> > > >
> > > >> the question is: do you know how to calculate
> > the sequential risk?
> > > >
> > > >You need the likelihood ratio from NT, first
> > trimester serum screening
> > and
> > > >second trimester serum screening.
> > > >
> > > >To respect the BAYES' rule, you have to multiply
> > the pre test risk
> > (1:411)
> > > >by the 3 likelihood ratios to calculate the
> > post-test risk.
> > > >
> > >
> > > I calculated these from the given numbers in the
> > original message and
> > > the cumulative risk is 1/2977
> > >
> > > --
> > > Best Wishes,
> > > R L Meisel, MD
> > >
> >
>
> =====
> David J. Berck, MD, MPH
>

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