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Re: Pyrosequencing technology -- Rapid test for Down Syndrome is successf From: Terry J. DuBose (duboseterryj@uams.edu) Thu Nov 14 07:32:12 2002 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: =?iso-8859-1?B?R/ZraGFuINZuY/xs?=: "Re: Abdominal calcifications" Previous message: Barbara Nesbitt, Publisher OBGYN.net: "Terry asked me to post this" Next in thread: art fougner, md: "Re: Pyrosequencing technology -- Rapid test for Down Syndrome is successf" Reply: art fougner, md: "Re: Pyrosequencing technology -- Rapid test for Down Syndrome is successf" Thanks, Shannon... I will forward this information. Terry BarringerShannonN@uams.edu writes: >I had recently heard about this---may have some promise, but still has not been proven in large scale studies...so those are underway now. Basically, there are small regions of DNA (SNPs or SNRPs) that are unique to different chromosomes...so instead of having to culture cells, and then count chromosomes in hundreds of cells, the lab is hoping to use radioactive probes that will "light"up within cells if they match up with specific SNPs. They apparently have made such probes for SNPs on >chromosome #21---and a "positive" test will show three copies of that particular SNP if a person has trisomy 21. > >May be promising! But still a ways off. > >Shannon > >-----Original Message----- >From: Terry J. DuBose [mailto:duboseterryj@uams.edu] >Sent: Wednesday, November 13, 2002 8:38 AM >To: BarringerShannonN@exchange.uams.edu; ButlerBeckyB@exchange.uams.edu >Subject: Fwd: Re: Pyrosequencing technology -- Rapid test for Down >Syndrome is successful; > >Have y'all heard anything about this? Thanks, Terry > >It appears to be lab related. I forwarded it to our lab for comment. > >Jeanette > >>>>> DuBose@io.com 11/12/02 04:51PM >>> >Is anyone familiar with this Dx test? >-- Rapid test for Down Syndrome is successful; other diagnostics >targeted -- > >http://www.pyrosequencing.com/news/pyro_geneva_expand_eng.htm > >One of my students asked about it, and I am clueless... or it's >statistical validity. > >Peace, Terry J DuBose > Peace, Terry J. DuBose, M.S., RDMS Assistant Professor & Director, Diagnostic Medical Sonography Program University of Arkansas for Medical Sciences, CHRP 4301 West Markham St. Mail Slot #563 Little Rock, Arkansas, 72205 USA 501-686-6510 DuBoseTerryJ@UAMS.edu http://www.io.com/~dubose/ http://www.uams.edu/CHRP/dmshome.htm http://www.obgyn.net/us/panel/panel.htm Next message: =?iso-8859-1?B?R/ZraGFuINZuY/xs?=: "Re: Abdominal calcifications" Previous message: Barbara Nesbitt, Publisher OBGYN.net: "Terry asked me to post this" Next in thread: art fougner, md: "Re: Pyrosequencing technology -- Rapid test for Down Syndrome is successf" Reply: art fougner, md: "Re: Pyrosequencing technology -- Rapid test for Down Syndrome is successf"

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