Re: Sonography & Cervical CA... Lit Search 8/29/02
From: udaya kumar (udaya@md2.vsnl.net.in)
Fri Aug 30 20:49:39 2002
Well Terry, to me it is just another study that tells us what we already know. Tumors have more blood vessels and offer less resistance to flow.
To perform an EVS and Powerdoppler to diagnose Ca Cervix is like touching your nose with your arm going around the head. Do it directly. Do a Pap smear, Cervical biopsy etc. Get definite proof and start treatment early.
Ultrasound can be used for assessing tumor extension in Ca Cx , NOT for diagnosis. Subclassifying this disease is of no practical use beacuse the treatment is the same.
Whatever the Power doppler finding, I am not going to consider postcoital bleed, foul smelling discharge and growth in the cervix as benign.
Dr.Udayakumar
Genesis Scans
Chennai, India.
"Terry J. DuBose" wrote:
> Is anyone familiar with this technique... or tried it? One of my students came up with this article, which I had not seen, and wants to know more about it.
>
> Thanks, Terry
>
> This article discusses the use of ultrasonagraphy along with Doppler to diagnose cervical carcinoma. This method detects the increased blood flow that is commonly found in malignancies. Compared to the procedures currently used to detect cervical cancer, this one is less invasive and more comfortable for the patient.
>
> Citation <1>
> Unique Identifier
> 11063641
> Medline Identifier
> 20519494
> Authors
> Wu YC. Yuan CC. Hung JH. Chao KC. Yen MS. Ng HT.
> Institution
> Department of Obstetrics and Gynecology, Veteran General Hospital-Taipei, 201, Section 2, Shih-Pai Road, Taipei, Taiwan, Republic of China.
> Title
> Power Doppler angiographic appearance and blood flow velocity waveforms in invasive cervical carcinoma.
> Source
> Gynecologic Oncology. 79(2):181-6, 2000 Nov.
> Local Messages
> Part @ UAMS (Click Library Holdings)
> Abstract
> OBJECTIVES: The aim of this study was to investigate the effectiveness of transvaginal power Doppler angiography in predicting cervical malignancy by detecting intratumoral blood flow and to understand the relationship between squamous cell carcinoma (SCC) serum levels and intratumoral blood flow analysis of invasive cervical carcinoma before treatment. METHODS: Thirty-eight patients with cervical carcinoma (35 with stages Ia to IVb invasive carcinoma, 3 with cervical carcinoma in situ) were
> enrolled for the evaluation of tumor flow using transvaginal ultrasound accompanied with power Doppler angiography before surgery. The pulsatility, resistance index, and vascular index of tumor flow were measured. Thirty patients with proven healthy cervices were used as the control group. Pretreatment SCC serum levels were obtained in 34 women with cervical carcinoma. RESULTS: The pulsatility index and resistance index were significantly lower in the study group than in the control group (P <
> 0.0001). The vascular index was
> also significantly lower in the study group than in the control group (P < 0.0001). There were no significant differences among patients with SCC type and non-SCC type cervical carcinoma (P > 0.05) among the six parameters. There was no significant correlation between the pretreatment SCC serum levels with any of the six parameters obtained from the intratumoral blood flow analysis in the SCC group. CONCLUSIONS: Transvaginal ultrasound with power Doppler angiography is a valuable diagnostic tool
> for differentiating b
> enign tumors of the cervix from malignant ones. Intratumoral blood flow of the cervix supplied us with practical diagnostic information before surgery and may aid in early prediction and management of cervical carcinoma. The use of transvaginal ultrasound with power Doppler angiography in the grading of vascularity ratio within cervical masses provided more sonographic characteristics among the different subclassifications of cervical cancer and is more useful than color Doppler imaging in the
> visualization of sonogr
> aphic morphology. Copyright 2000 Academic Press.
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