Re: Nuchal Translucency

From: Doc Gyn=?ISO-8859-1?B?6Q==?=co (jmbr@wanadoo.fr)
Thu Aug 23 12:52:59 2001


--> Message de Philippe Coquel :

> In theory with Nicolaides'data:
> With 1600 patients at 12 week, there are about 5.44 fetuses with nuchal
> translucency>3 mm.
> Among these fetuses, 2.08 have an aneuploidy (tri 21) and 3.36 are normal

The nuchal translucency goes beyond the first layer "genetics at a glance".

And to day we can write :

"Good news : the caryotype is normal. Bad news : the caryotype is normal" (Y. VILLE in Ultrasound Obstet Gynecol 2001; 18: 5-8).

1) equal amount will suffer from another aneuploidy such as turner or edwards syndrome

2) and from 14 % (NT 3,5 to 4,4 mm) to 69 % (NT > 6,4 mm) will run into some adverse outcome (fetal defects (CVS), spontaneous abortions, intrauterine deaths and so on)

The chance of a livebirth with no defects in the group with NT of :

3.5-4.4 mm was 86%

4.5-5.4 mm it was 77%

5.5-6.4 mm it was 67%

6.5 mm and more it was 31%

SOUKA A.P «Outcome of pregnancy in chromosomally normal fetuses with increased nuchal translucency in the first trimester» Ultrasound Obstet Gynecol 2001;18:9-17

--
Bien tropicalement,
Dr J-M BRIDERON (MD) Gyn-Obs
ECHOLIST :  liste de diffusion sur l'echographie gyn-obs
http://www.gyneweb.fr/echolist.htm



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