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Re: Fetal lung maturityFrom: DuboseTerryJ@uams.eduWed Jul 11 16:55:42 2001
Dear Dr. D'Angelo, your question is an excellent one... one that really needs a solution. If someone could come up with a foolproof method of determining fetal lung maturity using ultrasound they would win the whole set of dishes! A long time ago, in the Dark Ages of sonography, before 1985 there were some papers that proposed that lung maturity might be assessed by comparing it to the liver. The theory was that when the alveoli started filling out the lung would go from being less echogenic than the liver to being more echogenic. Unfortunately, subsequent studies found it to be a very unreliable technique. At the 1998, Edinburgh, Scotland, 8th World Congress on Ultrasound in Obstetrics & Gynecology, there was a Fetal Lung: Round Table Discussion. I have a brief review of this panel discussion at: http://www.obgyn.net/us/us.asp?page=/us/news_articles/ISUOG/Fetal-Lung . In this review I give a brief description of each research project, world wide, that is trying to solve the lung maturity quandary. (Unfortunately, the links to the photographs of some of the panel members and some of their slides are broken... hopefully repaired soon. ) There were reports of research on fetal lung maturity and Doppler of the pulmonary arteries and veins in an attempt to solve this problem. No definite results yet, but it is a promising direction to go. My gestalt tells me that there should be some change in the pulmonary perfusion when the lungs mature...probably a drop in the RI, but we need someone to figure out how to do that. Others were trying to use Doppler to measure or estimate the rate of fluid movement in fetal breathing motions... also not successful yet. Sorry I can't give you a better answer. Peace, Terry J. DuBose, M.S., RDMS, APS Assistant Professor & Director, Diagnostic Medical Sonography Program CHRP, University of Arkansas for Medical Sciences Little Rock, Arkansas, USA 501-686-6510 http://www.io.com/~dubose/ http://www.uams.edu/CHRP/dmshome.htm http://www.obgyn.net/us/panel/panel.htm -----Original Message----- From: Pablo D'Angelo [mailto:pjd@post.com] Sent: Wednesday, July 11, 2001 3:26 PM To: Multiple recipients of list ULTRASOUND Subject: Fetal lung madurity Hello Someone knows if there is any RELIABLE way to determine fetal lung madurity with ultrasound? We had a pregnant woman 26 weeks of gestation with premature rupture of membranes from 4 weeks ago, with an AFI that never exceeded 10 mm. We need to know lung madurity. Any idea? Thanks
-- Pablo D'Angelo, MD from Argentina
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