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Re: Renal Agenesis and Noncystic Renal Dysplasia - Hypovolemic shock??From: James S. Smeltzer, MD (gaperina@mindspring.com)Sun May 20 11:54:12 2001
Rich, the urine present and urine production in response to lasix and weight loss, vomiting indicate that the infant may have hypovolemic shock from intestinal obstruction or necrosis as the main problem. If K is LOW this is true. If K is high then intrinsic renal disease is more likely. An easy way to tell the difference is to look at the heart. If filling is lousy then baby is dry. If overfull then volume is overloaded, which I doubt given the history. It is sort of urgent, as ATN is the last thing this baby needs to add to her problems. Re: Gut malrotation and renal problem there are two X-Linked: X-linked Vater and Opitz G/BBB syndrome, ruled out by sex in this baby. Cat eye syndrome may have malrotation and renal dysplasia (Inv dup 22 q11), but other stigmata are prominent. Pallister-Hall syndrome (Mapped to 7p13) has many CNS problems and extremity abnormalities you do not mention. The laterality sequence is also sex-linked, and typically does not include renal problems. I cannot find a good fit for the malrotation renal aplasia with no other findings. Good luck! Jim S
>----- Original Message -----
> Scanned a 7 day old female infant,(born at 38 weeks prematurity) with a
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