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Re: Alpha ThalassemiaFrom: James S. Smeltzer, MD (gaperina@mindspring.com)Tue Jan 16 20:14:29 2001
The Delta is the difference from a baseline curve. OD is optical density. 450 is at 450 nanometers. So it is the increased absorbance at 450 nm versus elsewhere in the spectrum. This is the classical way to measure bilirubin in the amniotic fluid, and the basis of Liley's curve and Zones of fetal risk of this value versus gestational age. I apologize for the jargon. Jim Smeltzer
> ----- Original Message ----- Dear Sir, What is delta OD450, Dr. Fazeel "James S. Smeltzer, MD" wrote: Terry, The VMax is EGA dependent. I have a chart of the MoM curves used in that analysis. of 24 today). I stopped the amniocenteses for delta OD450, after Labcorp messed up two consecutive specimens - both through freezing them. Once the just like sickle cell - because the trait gives a large selection advantage from clearing the intraerythrocytic stage of malaria parasites, or so I am told.
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